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Chromatography System
Liquid Chromatography Systems

VION FAST LIQUID CHROMATOGRAPHY SYSTEM

The Vion Liquid Chromatography System offers quaternary solvent blending and advanced separation performance. It is specifically designed for routine analysis, research and method development, making it ideal for fast liquid chromatography applications that demand high resolution and sensitivity.

VION FAST LIQUID CHROMATOGRAPHY SYSTEM - Professional laboratory equipment
Product Overview

The Vion Liquid Chromatography System offers quaternary solvent blending and advanced separation performance. It is specifically designed for routine analysis, research and method development, making it ideal for fast liquid chromatography applications that demand high resolution and sensitivity. The system features a quaternary pump with an online degasser, a precise injector, and is compatible with various detectors, including UV, PDA, fluorescence (FLR), refractive index (RI), and evaporative light scattering detectors (ELSD). It also supports columns with particle sizes as small as 1.7 microns and can handle high-pressure operations. Additionally, the Vion system is fully compatible with mass spectrometers, delivering accurate and reliable results for complex analytical workflows.

Key Features & Advantages
Discover what makes this system exceptional for your laboratory needs
Quaternary Solvent Blending: Advanced quaternary pump system with online degasser for precise solvent mixing and consistent mobile phase delivery
High-Pressure Capability: Supports high-pressure operations for use with sub-2 micron particle columns, enabling enhanced separation efficiency
Multi-Detector Compatibility: Compatible with UV, PDA, fluorescence (FLR), refractive index (RI), and evaporative light scattering detectors (ELSD), MS, HRMS.
Mass Spectrometer Integration: Fully compatible with mass spectrometers for comprehensive analytical workflows
Precision Injection System: High-precision injector ensures accurate and reproducible sample introduction
Advanced Column Support: Supports columns with particle sizes as small as 1.7 microns for superior resolution
Instrument Specifications
Detailed technical specifications and performance parameters
ParameterSpecification
Quantum synchronizationInjection synchronization between pump and sample manager enhances retention time reproducibility
Flow rate range0.001 to 2.000 ml/min with increment of 0.0001 ml/min
pH range1 to 13
Cycle time≤20 s inject-to-inject
Maximum operating pressure18,000 psi
Leak sensorsAvailable
Dwell volume (total system)≤350 µL
Gradient delay volume≤310 µL
Solvent configurationFour-solvent low-pressure gradient
Gradient typeQuaternary gradient, Low-pressure mixing
Gradient profiles12 gradient curves
Pressure pulse≤1.0%
Number of solvents4
Solvent degassingAutomated vacuum degassing
Solvent mixingAutomated
Pump flow rate range0.01 to 2.0 ml/min
Flow precision≤0.070% RSD
Flow accuracy±1.0%
Composition precision≤0.10% RSD
Composition accuracy±0.25%
Pump seal washAutomated Seal wash
Automated primingYes
Sample platesAny two of the following: 96 and 384 microtiter plates, 48 position 2.00-ml vial plates
Injection methodTotal-volume sample injection
Injection precision≤1% RSD
Injection accuracy±0.1 µL
Injection linearity≥0.9999
Injection volume range0.1 to 100.0 µL
Advanced sample managerAuto-dilution and Auto-addition
Injection needle washIntegral, active, programmable
Sample compartment temperature4.0 to 45.0 °C, settable in 0.1 °C increments
Sample temperature accuracy±0.5 °C at sensor
Sample temperature stability±1.0 °C at sensor
Sample carryover≤0.002% caffeine (UV)
Column capacityTwo columns
Column heating/coolingForced air circulation method
Solvent conditioningActive pre-heating
Column trackingYes
Column compartment temperature stability±0.2°C
Column compartment temperature range4.0 to 110.0°C, settable in 0.1°C increments
Column compartment temperature accuracy±0.5°C
Sample organizer temperature accuracy±1.0 °C at the sensor
Sample organizer temperature stability±1.0 °C at the sensor
External controlSpera Analytical Software

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